Role of tranexamic acid (TXA) administered locally into the surgical site intraoperatively in reducing the post-operative blood loss in hip Arthroplasty

Author(s): Dr. Md Jaanbasha, Dr. C Shamsundar and Dr. Lalitmohan

Abstract: Total hip arthroplasty (THA) has revolutionized the quality of life of men and women of all ages since the 1960s, earning the title of “the operation of the century. Being a measure surgery there is considerable loss of blood in intra and post operative period along with drop in the level of hemoglobin. Average blood loss is around 1000ml (450 to 1900ml) and the mean hemoglobin fall is 2.1 ± 1.1 g/dl. There are various methods available to control and decrease the blood loss intra and post operatively. Systemic administration of tranexamic acid has been studied and its effectiveness being proved in literature and commonly being used in orthopedics, gynecology and neuro surgery. But, Administration and the effects of tranexamic acid into the operative site haven’t been published in literature, to the best of our knowledge. Present study is based on the estimation of effectiveness of TXA at the surgical site after wound closure.

DOI: https://doi.org/10.22271/ortho.2020.v6.i4j.2404