Abstract: 49 year old female who underwent curettage and cementation for distal femur Giant cell tumor (GCT) 16 years back, presented with severe knee osteoarthritis. She was managed with navigation assisted primary total knee replacement with cruciate retaining prosthesis. The possibility of cement augment loosening with drilling intramedullary canal was also ruled out when navigation system was employed.
Theoretical contamination of the femoral canal by residual tumor can be avoided by using navigation. Primary cementation during management of GCT and employment of navigation system provides optimal outcomes.