Abstract: Background: Osteoporosis is a major public health problem as it is associated with substantial morbidity and socioeconomic burden.
Aims and Objective: To correlate the age at menopause with bone mineral density in post menopausal woman.
Materials and Methods: Two hundred postmenopausal women were studied at the Department of Obstetrics and Gynaecology, King Georges Medical University, Lucknow, between September 2015 to August 2016. A detailed questionnaire was filled which included details of demographic factors of the patient, detailed reproductive history including parity, number of living children, age at menarche, age at menopause, years since menopause, whether menopause was natural or surgical. BMD was measured in each woman at lumbar spine (L1-L4) by lunar Prodigy dual energy X Ray absorptiometry.
Results: A total of 72 (36%) women had osteopenia and remaining 123 (61.5%) had osteoporosis. Only 5 (2.5%) women had normal BMD status. Maximum (n=121) were in the 51-60 years age group. There was no significant relation between age and BMD. Proportion of women with osteoporosis was significantly higher in rural (70.3%) as compared to urban (41.9%) areas (p=0.001). Osteoporosis was seen in 82.6%women with > 4 parity (p=0.049). Mean age of menopause in women with normal BMD, osteopenia and osteoporosis was 44.60, 45.51and 43.85 years respectively. No significant association between period since menopause and BMD status could be seen. No significant association was observed either for total or for any of the BMD strata (p>0.05).With increasing duration since menopause a significant decline in T scores was observed (p=0.023) on overall assessment. However, this association was not significant statistically for different BMD strata (p>0.05).
Conclusion: The prevalence of osteoporosis was higher as compared to the world prevalence. The correlation between the age at menopause and BMD was significant in accordance with the various worldwide studies.
