International Journal of Orthopaedics Sciences

Analysis of pattern of change of VAS and WOMAC between autologous bone marrow derived mesenchymal stem cells enhanced with platelet rich plasma versus platelet rich plasma in osteoarthritis knee

2017, Volume 3 Issue 1

Analysis of pattern of change of VAS and WOMAC between autologous bone marrow derived mesenchymal stem cells enhanced with platelet rich plasma versus platelet rich plasma in osteoarthritis knee

Author(s): Dr. Sunil Kumar TR and Dr. Harish YS
Abstract: Introduction: Osteoarthritis (OA) is a chronic degenerative disorder that is characterized by a loss of articular cartilage, in the synovial joints which is characterized by sclerosis subchondral bone thickening, marginal osteochondral outgrowths (osteophytes). Several risk factors have been identified, such as obesity, occupation, higher age, biomechanics and increased dynamic loading of the joint and joint injury, and invoves the weight bearing joints like hip and knee joint
Methodology: The sample size studied was 32 patients of which 16 patients in each group.The patients were selected after going through the inclusion and exclusion criteria. The patients were examined clinically regarding VAS score KOOS score and WOMAC score recorded each patient was investigated by routine blood tests investigation X ray, MRI
Results: The group 1 had baseline pain score of mean 9.38 with (SD±2.187) and in group 2 had baseline pain score of mean 9.13 (SD±1.586). Both groups were comparable and were statistically significant with p value of 0.571. At final follow up, WOMAC score of group 1 had mean 1.25 (SD±0.557) and group 2 had mean of 1.00 (SD±0.00), It was not significant (p= 0.74).
Conclusion: A trend towards gradual and progressive decline of the VAS is noted in the patients over the period of three follow ups from the baseline score
Pages: 658-663  |  1532 Views  112 Downloads
How to cite this article:
Dr. Sunil Kumar TR, Dr. Harish YS. Analysis of pattern of change of VAS and WOMAC between autologous bone marrow derived mesenchymal stem cells enhanced with platelet rich plasma versus platelet rich plasma in osteoarthritis knee. Int J Orthop Sci 2017;3(1):658-663. DOI: 10.22271/ortho.2017.v3.i1j.97
 
International Journal of Orthopaedics Sciences
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