International Journal of Orthopaedics Sciences

Effect of Habbe Gule Aakh in osteoarthritis knee: A randomised clinical trail

2024, Volume 10 Issue 2

Effect of Habbe Gule Aakh in osteoarthritis knee: A randomised clinical trail

Author(s): Dr. Mubasheera Begum, Dr. Aleemuddin Quamri and Dr. V. Habibullah
Abstract: 
Background: Osteoarthritis of knee is a chronic degenerative disorder of multifactorial etiology characterized by the loss of articular cartilage, hypertrophy of bone at the subchondral sclerosis. Osteoarthritis knee is managed effectively in Unani system of medicine with Habbe Gule Aakh
Objective: To evaluate the study of different doses of Habbe Gul Aakh in osteoarthritis knee joint
Methods: A randomized single blind parallel arm comparative (dose escalation) study. Habbe Gule Aakh was administered in different doses on 60 patients of osteoarthritis knee in National Institute of Unani Medicine, Bengaluru. Four groups with 15 patients in each, were divided based on Radiological Kellgren Lawrence scale. The subjects of Group I were administered orally with 500 mg, Group II with 1000 mg, Group III with 1500 mg and Group IV with 2000 mg Habbe Gule Aakh, per day in 2 divided doses. The effect of study was assessed with objective parameters of WOMAC (Modified) CRD Pune Questionnaire, Visual Analogue Scale (VAS) was analyzed on 0th, 7th, 14th and 21st day. The data was analysed by ANOVA test, paired t-test, Student t test, and Chi-square/Fisher Exact test for intragroup and intergroup comparisons
Results: The observation of the study reveals that H.G.A orally in group I, II, III and IV for a period 21 days dose escalated as per Grades shows significant improvement(p<0.001) in patients of all groups with objective parameters of WOMAC (modified) Pune Questionnaire and VAS without any adverse effects
Trial registration: Committee (IEC No: NIUM/IEC/2019-20/007/Moal/07 DT 24.09.2020 and registered in CTRI: CTRI/2021/03/031747.

Pages: 40-48  |  257 Views  139 Downloads


International Journal of Orthopaedics Sciences
How to cite this article:
Dr. Mubasheera Begum, Dr. Aleemuddin Quamri, Dr. V. Habibullah. Effect of Habbe Gule Aakh in osteoarthritis knee: A randomised clinical trail. Int J Orthop Sci 2024;10(2):40-48. DOI: 10.22271/ortho.2024.v10.i2a.3530
 
International Journal of Orthopaedics Sciences
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