The effect of thyroid hormone dysfunction on bone’s metabolism

Author(s): Dr. Jeff Walter Rajadurai OR, Dr. Karthick Balusamy, R Varadhan, Sharon Ann Varghese and Sheba Salome T

Abstract: Decreased bone mineral density due to osteoporosis is the main cause of fragility fractures and leads to reduced quality of life. This can cause increased morbidity and mortality. Disturbance of balance between bone formation and bone resorption is dangerous. It can cause loss of bone mass and disruption of it’s architecture. Correct development, achievement of peak bone mass and normal functioning of human skeleton depend on different factors. Thyroid harmones play an important role in bone metabolism. Both excess as well as deficiency of fT₄ and fT₃ can be

DOI: https://doi.org/10.22271/ortho.2020.v6.i3c.2186