Vol. 11, Issue 4 (2025)

Background: Osteoarthritis (OA) is a common long-term condition that greatly contributes to disability among older adults. This disorder influences the entire joint, making it particularly difficult to regenerate articular cartilage, especially when active inflammation is present. Being a key weight-bearing joint, the knee is especially prone to OA, which makes it one of the foremost contributors to disability around the globe. Despite its extensive effects, there have been impressive advancements in treatment options in recent years.
Methods: The prospective observational study was conducted in four sites which included 150 patients and evaluated a total of 216 knees that received total knee arthroplasty (TKA) with the EXCEL MEDIAL PIVOTAL KNEE SYSTEM (EMPK) prosthesis. Clinical outcomes were assessed utilizing established patient-reported outcome measures (PROMs), including the Knee Society Score (KSS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and Oxford Knee Score (OKS), both prior to the surgery and six months following it.
Results: The study involved an average age of 65.7±7.19 years with a greater proportion participated by female patients. After six months post-surgery assessment the mean Oxford Knee Score (OKS) rose significantly from 13.4±3.5 prior to surgery to 30.0±4.1 (p<0.001). The average Knee Society Score (KSS) improved from 52.3±16.4 to 138.9±15.2 (p<0.001 and the mean Western Ontario and McMaster Universities Arthritis Index (WOMAC) score reduced from 67.22±8.80 to 41.43±7.75 (p<0.001), demonstrating significant advancements in functional mobility and pain alleviation.
Conclusion: The six-month postoperative data uncovers that EMPK propounds a notable improvement in knee functions in patients experiencing end stage OA. Nevertheless, it is essential to focus on effective postoperative care, predominantly in post-operative infection and implant durability.