Melorheostosis is a rare chronic bone disease, characterized by linear hyperostosis along the bone cortex. First case described in 1922 by Leri and Joanny. It can affect any bone, being more frequent in long bones. The etiology remains unknown although several theories have been proposed. Men and women are equally affected, and no hereditary features have been discovered. Onset is insidious, and mostjj common symptoms are pain, deformity and joint stiffness. The diagnosis is obtained by combining the clinical and radiological findings (mainly radiography with typical image in "candle wax"). There is no definitive or specific treatment, being always palliative.
Case report: We describe a case of a 35-year-old woman presented with a history of left forearm dull and aching pain with mild swelling. There was no relevant family history or trauma. Physical examination revealed a firm non-tender swelling over distal half of the left forearm. The pathology report described nonspecific, dense cortical bone with mature and immature bone tissues. X-rays showed hyperostosis of the radius of the right forearm (image in "candle wax"). The patient is in physical therapy program and has a positive response to analgesics and intravenous bisphosphonate zolendronic acid.
Conclusion: The exact etiology remains unclear. There is no definite treatment available for this rare disease. Only symptomatic treatment improve the condition of the patients, quit well result obtain with zolendronic acid and physiotherapy.